Abstract |
In the present communication, the results will be
reported on a clinical study of how well scintigraphic
visualization of the hepatobiliary elements and several
commonly used clinical liver function tests correlate
each other in various diseases of hepatobiliary system.
The demonstrability of the biliary tract, gallbladder
(GB) and duodenum was rather closely paralleled to
serum bilirubin level and less closely to alkaline
phosphatase and rather poorly to SGOT and SGPT. The
usefulness of Tc-99m EHIDA [N-(2,6-diethylacetanilido)
iminodiacetic acid, made by Amersham, England]
hepatobiliary scintigraphy (Tc EHIDA HBS) in settling
diagnostic controversy and ambiguity raised by oral
cholecystography, intravenous cholangiography and
ultrasonography in many hepatobiliary diseases is well
known. The purpose of this investigation was to
semiquantitatively evaluate the scintigraphy
demonstrability of the hepatobility tract, GB and
duodenum following intravenous injection of Tc-99m-
EHIDA in normal subjects and in patients with a
disturbed liver function from various hepatobility
diseases. The hepatobiliary scintigraphy was performdd
in 10 normal subjects and 39 patients with various
hepatobiliary diseases(Table 1) at the Dept. of
Radiology, St. Mary's Hospital Catholic Medical
College, Seoul, Korea during 2 years period from
September 1979. Scintigraphy examination was started at
end of 3 minutes after intravenous injection of Tc-99m
EHIDA in the amount of 50 μCi/kg and was continued
until after 30 minutes at 5 minutes interval. The
imaging was usually terminated when the tracer could be
seen in the duodenum. Late scintigrams were obatained
at 11/2, 2, 3, 4 and 6 hours when n,eeded. Scintigrams
were analyzed in terms of promptness and clarity of
visulization of the biliary tree, GB and duodenum and
demonstrability of these anatomical landmarks was
correlated with the values of liver function tests. The
demonstrability of the common hepatic duct, common bile
duct, GB and duodenum was closely paralleled to the
level of ser |