원저 : Tc-99m-MIBI 심근 SPECT 극성지도 분석에 의한 심근 기능의 정량적 평가 ( A Quantitative Method for the Assessment of Myocardial Function using the Polar Analysis of Tc-99m-MIBI Myocardial SPECT ) () |
Author |
곽철은(Cheol Eun Kwark),이동수(Dong Soo Lee),여정석(Jung Suk Yeo),이경한(Kyung Han Lee),정준기(June Key Chung),이명철(Myung Chul Lee),서정돈(Jung Don Seo),고창순(Chang Soon Koh), |
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Affiliation |
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Abstract |
As the Tc-99m-MIBI myocardial SPECT demonstrated wide
application in the diagnosis of myocardial function the
quantitative and severity-dependent information is
currently required. In this study, we proposed a
computerized method for scoring the fixed devects in
terms of extent-weighted severity and for identifying
the reversibility in ischemic regions. At the first
stage of this method, the transverse slices were
reconstructed with (1.4 Nyquist freq. and order 5
Butterworth filter. From the oblique/sagittal slices,
maximal count per pixel circumperential profiles were
extracted for each sector, and then stress/ redist.
polar maps were normalized and plotted. For
reversibility, the stress polar map was subtracted from
the delayed miage and positive-valued pixels were
categorized into three grades. The extent-weighted
seerity scores were calculated using the assigned
grades and their number of pixels. This procedure was
done automatically and the reversibility and severity
scores were produced for each of the coronary
territories (LAD, RCA, LCX) of any combination of
these. Clinical application has shown that the changes
in reversibility scores after PTCA were correated
linearly with the pre PTCA scores(r>0.8) in postinfarct
cases as well as in angina, and seerity scores of
persistent devects in stress/rest SPECT study matched
to the regional ejection fraction and visual analysis
of regioal wall motion of gated blood pool scan(r>0.6).
We conclude that the computerized severity scoring
method for the analysis of myocardial SPECT could be
useful in the assessment of the myocardial ischemia and
fixed defect. |
Keyword |
Tc-99rn-MIBI myocardial SPECT, Polar analysis, extent-weighted severity score, Reversibility |
Full text Article |
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