원저 : 휴식 / 부하 심근 Rubidium - 82 양전자단층촬영과 부하 / 휴식 심근 Tc - 99m - MIBI 단일광자단층촬영의 비교 ( Stress / Rest Tc - 99m - MIBI SPECT in Comparison with Rest / Stress Rubidium - 82 PET ) () |
Author |
이동수(D . S . Lee),강건욱(K . W . Kang),이경한(K . H . Lee),정재민(J . M . Jeong),곽철은(C . Kwark),정준기(J . K . Chung),이명철(M . C . Lee),서정돈(J . D . Seo),고창순(C . S . Koh), |
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Affiliation |
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Abstract |
We compared stress/rest myocardial Tc-99m-MIBI
tomographic image findings with rest/stress rubidium-82
tomographic images. In 23 patients with coronary artery
disease (12 of them received bypass grafts before) and
6 normal subjects, rest rubidium PET study was
performed, rubidium-82 and Tc-99m-MrBI were injected
simultaneously to each patient after dipyridamole
stress for rubidium PET and MIBI SPECT; and rest MIBI
SPECT was performed 4 hours thereafter. We scored
segmental decrease of rubidium, or MIBI uptakes into 5
grades for 29 segments from 3 short-axis, vertical and
horizontal slices. Scores were summed for each major
arterial territory. When more score than two grade-2's
or one grade-3 was considered as the cue for
significant stenosis for major arterial territories,
67% of 46 stenosed arteries were found with MIBI
studies and 78% of them by rubidium studies. Fourteen
among 28 grafted arterial territories of 12 post-CABG
patients were found normal with both rubidium and MIBI.
Segmental scores were concordant between rubidium and
MIBI in 72% of 709-stress segments and in 80% of 825
rest segments. Stress rubidium segmental scores were
less than stress MIBI scores in 9%, so were rest
rubidium scores. Stress rubidium scores were more than
stress MIBI scores in 20% of segments, and rest
rubidium segmental scores were more than rest MIBI
scores in 11%. Rank correlations (Spearman's rho's more
than 0.7(stress) and 0.5(rest), slopes (MIBI/rubidium)
around 0.7(stress) and 0.9(rest) suggested deeper and
wider defects in stress with rubidium. Slope over 1
(MIBI/rubidium) with LAD segemental scores at rest and
7 territories which had much larger score with MIBI
revealed exaggeration of rest defects with rest MIBI in
same-day stress/rest study. Difference scores (stress-
rest for each territory) suggesting ischemia were
larger with rubidium (slope of MIBI/rubidium around
0.45). As has been implied by animal or separate-day-
human studies, these segmental analyses with
simultaneous examination in patients told that rubi |
Keyword |
Tc-99m-MIBI SPECT, Rb-82 PET, Dipyridamole stress, Segmental analysis |
Full text Article |
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