원저 : Sturge - Weber 증후군의 뇌관류 SPECT 영상 : 자기공명영상과의 비교 ( Brain Perfusion SPECT Imaging in Sturge - Weber Syndrome : Comparison with MR Imaging ) () |
Author |
류진숙(Jin Sook Ryu),최윤영(Yun Young Choi),문대혁(Dae Hyuk Moon),양승오(Seoung Oh Yang),고태성(Tae Sung Ko),유시준(Shi Joon Yoo),이희경(Hee Kyung Lee), |
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Affiliation |
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Abstract |
자가면역성 갑상선질환에서의 혈청 Thyrotropin-Binding
Inhibitine Immunoglobulin치
In order to evaluate the significance of thyrotropin-
binding inhibiting immunoglobulin
(TBII) in the patients with autoimmune thyroid
diseases, the authors investigated 402
cases of Graves' disease and 230 cases of Hashimoto's
thyroiditis comparing 30 cases
of normal healthy adult at Kyung Pook University
Hospital from February 1993 to
August 1994. The TBII was tested by radioimmunoassay
and assesed on the dynamic
change with the disesase course, thyroid functional
parameters, and other thyroid
autoantibodies; antithyroglobulin antibody(ATAb) and
antimicrosomal antibody(AMAb)
including thyroglobulin. The serum level of TBII was
40.82±21.651(mean±SD)% in
hyperthyroid Graves' disease and 8.89±14.522% in
Hashimoto's thyroiditis and both
were significant different from normal control of which
was 3.21±2.571%. The frequency
of abnormally increased TBII level was 92.2% in
hyperthyroid Craves' disease, 46.7% in
euthyroid Graves' disease or remission state of
hyperthyroidism, and 23.9% in
Hashimoto's thyroiditis. The serum levels of increased
TBII in Graves' disease were
positively correlated with RAIU, serum T3, T4, and FT4,
but negatively correlated with
serum TSH(each p〈0.001). The TBII in Graves' disease
had significant positive
correlation with serum thyroglobulin and AMAb, but no
significant correlation with
ATAb. In the Hashimoto's thyroiditis, the serum levels
of TBII were positively
correlated with RAIU, serum T3, TSH and AMAb, but not
significantly correlated with
serum T4, FT4, thyroglobulin and ATAb. Therefore serum
level of TBII seemed to be a
useful mean of assessing the degree of hyperthyroidism
in Graves' disease and
correlated well with thyroidal stimulation. The serum
level of TBII in Hashimoto's
thyroiditis is meaningful for the degree of both
functionl abnormality reflecting either
hyperfunction or hypofunction and the immunologic
abnormality. |
Keyword |
Sturge-Weber syndrome, 99mTc-HMPAO, 99mTc-ECD, Brain perfusion SPECT, MRI |
Full text Article |
28501623.pdf
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