Abstract |
It has been shown that both rest and stress myocardial
perfusion imagings with technetium agents can be
performed on the same day using two different doses
injected within few hours. The purpose of this study
was to compare the two protocols (stress-rest and rest-
stress) in detecting coronary artery diseases. One
hundred and sixty patients (101 males, 59 females, mean
age 57±9 years) and 120 patients (79 males, 41
females, mean age 59±10 years) underwent stress-rest
myocardial perfusion SPECT and rest-stress myocardial
perfusion SPECT, respectively All of them underwent
both myocardial perfusion SPECT and coronary
angiography within 1 month. A coronary stenosis was
considered significant when it compromised the luminal
diameter by≥50%. The chi square test was used to
compare differences in sensitivity, specificity and
accuracy between the two groups. The overall
sensitivity, specificity and accuracy of stress-rest
protocol were 99%, 35%and 68%, respectively. Those of
rest-stress protocol were 96%, 47%, and 78%,
respectively. There was no difference between the two
protocols in identifying individual diseased coronary
artery branches. Therefore, one day stress-rest and
rest-stress myocardial SPECT using Tc-99m agents were
comparable and were very sensitive tests in detecting
coronary artery diseases. |