원저 : 게이트 Tc-99m-MIBI SPECT 와 Cedars 소프트웨어를 이용한 심근 기능 측정의 재현성 ( Reproducibility of the Assessment of Myocardial Function Using Gated Tc-99m-MIBI SPECT and Quantitative Software ) () |
Author |
이명철(Myung Chul Lee),정준기(June Key Chung),이동수(Dong Soo Lee),안지영(Ji Young Ahn),천기정(Gi Jeong Cheon), |
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Affiliation |
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Abstract |
Purpose: We investigated reproducibility of the
quantification of left ventricular volume and ejection
fraction, and grading of myocardial wall motion and
systolic thickening when we used gated myocardial SPECT
and Cedars quantification software. Materials and
Nethods: We performed gated myocardial SPECT in 33
consecutive patients twice in the same position after
Tc-99m-MIBI SPECT. We used 16 frames per cycle for the
gatingof sequential Tc-99m-MTBI SPECT. After
reconstruction, we used Cedars quantitative gated SPECT
and calculated ventricular volume and ejection fraction
(EF), Wall motion was graded using 5 point score. Wall
thickening was graded using 4 point score. Coefficient
of variation for re-examination of volume and fraction
were calculated. Kappa values (k-value) for assessing
reproducibility of wall motion or wall thickening were
calculated. Results: Enddiastolic volumes (EDV) ranged
from 58 mi to 248 ml (122 ml +/- 42 ml), endsystolic
volumes (ESV) from 20 mi to 174 mi (65 ml +1- 39 ml),
and EF from 20% to 68% (51% +/- 14%). Geometric mean of
standard deviations of 33 patients was 5.0 ml for EDV,
3.9 ml for ESV and 1.9% for EF. Their average
differences were not different from zero (p>0.05). k-
value for wall motion using 2 consecutive images was
0.76 (confidence interval: 0.71-0.81). k-value was 0.87
(confidence interval:0.83-0.90) for assessment of wall
thickening. Conclusion: We concluded that
quantification of functional indices, assessment of
wall motion and wall thickening using gated Tc-99m-MIBI
SPECT was reproducible and we could use this method for
the evaluation of short-acting drug effect. |
Keyword |
Tc-99m MIBI, Heart, Left ventricular ejection fraction, Reproducibility |
Full text Article |
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