Rhenium-188 방사성 의약품 ( Labelling with Rhenium-188 ) () |
Author |
최연성(Yearn Seong Choe), |
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Affiliation |
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Abstract |
There is considerable interest in 188Re due to its
favorable properties as a therapeutic radionuclide.
188Re and 99mTc act as a matched pair because of their
similar chemical properties, and therefore methods of
labeling with 99mTc can be applied to the labeling with
188Re. With appropriately chosen agents as carriers of
188Re, the labeling can be readily carried out using
188ReO4- in the presence of a reducing agent. 188Re
radio pharmaceuticals based on 99mTc complexes have
been synthesized and are currently being studied for
clinical use. Some of them are shown to be suitable for
therapeutic use and promising for radiotherapy in
nuclear medicine. |
Keyword |
Re-188, Tc-99m, Radiopharmaceuticals, Radiotherapy |
Full text Article |
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