암환자의 추적 골스캔에서 관절주위 섭취증가시 전신골섭취계수 측정이 골수전이 평가에 도움이 되는가-골수스캔과의 비교 (The Usefulness of Measurement of Whole Body Count in Assessing Bone Marrow Metastasis in Cancer Patients with Increased Periarticular Bone Uptake on Follow-up Bone Scan: A Comparison with Bone Marrow Scan) |
Author |
진성찬,최윤영,조석신, |
Seongchan Jin, M.D.,Yun Young Choi, M.D.,Sukshin Cho, M.D. |
Affiliation |
한양대학교 의과대학 핵의학 교실, 진단방사선과학교실 Department of Nuclear Medicine and Diagnostic Radiology, Hanyang University College of Medicine, Seoul, Korea |
Abstract |
Purpose: Increased periarticular uptake could be associated with peripheral bone marrow expansion in
cancer patients with axial bone marrow metastasis. We compared bone scan and bone marrow scan to
investigate whether the increased whole body count in patients with increased periarticular uptake on bone
scan is useful in the diagnosis of axial marrow metastasis, and evaluate the role of additional bone marrow
scan in these cases. Materials and methods: Twelve patients with malignant diseases who showed
increased periarticular uptake on bone scan were included. Whole body count was measured on bone scan
and it is considered to be increased when the count is more than twice of other patients. Bone marrow
scan was taken within 3-7 days. Results: Five hematologic malignancy, 3 stomach cancer, 2 breast
cancer, 1 prostate cancer and 1 lung cacner were included. All three patients with increased whole body
count on bone scan showed axial marrow suppression and peripheral marrow expansion. Eight of 9 patients
without increased whole body count showed axial marrow suppression and peripheral marrow expansion.
One turned out to be blastic crisis of chronic myelogeneous leukemia, and seven showed normal axial
marrow with peripheral marrow expansion in chronic anemia of malignancy. The last one without increased
whole body count showed normal bone marrow scan finding. Conclusion: Increased whole body count on
bone scan could be a clue to axial bone marrow metastasis in cancer patients with increased periarticular
uptake, and bone marrow scan is a valuable method for differential diagnosis in these cases. |
Keyword |
Tc-99m MDP, Tc-99m tin colloid, Bone scan, Bone marrow scan, Bone marrow metastasis, |
Full text Article |
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