일측 성대마비 환자의 보상기전에 관여하는 후두내근육 : PET-CT 융합 영상을 사용한 정상군과의 발성시 및 비발성시의 비교 (Departments of 1Radiology and 2Otolaryngology, Ewha Womans University College of Medicine, Seoul, Korea) |
Author |
배문선1,김현경2,김한수2, |
Moonsun Pai, M.D.1, Hyon Kyong Kim M.D.2, and Han Su Kim M.D.2 |
Affiliation |
이화여자대학교 의과대학 목동병원 방사선과1, 이비인후과2 Hypermetabolism of Compensatory Laryngeal Muscles in Unilateral Vocal Cord Palsy: Comparison Study between Speech and Silence with Normal Subjects by Co-registered PET-CT Fusion Images |
Abstract |
Purpose: There are a few case reports on asymmetric vocal cord uptake on FDG-PET in patients with unilateral
vocal cord paralysis, which could be a potential pitfall in the interpretation of FDG-PET images. We evaluated the
metabolic activity of laryngeal muscles of patients with unilateral vocal cord paralysis in comparison to normal
controls during both speech and silence. Methods: Eleven patients with unilateral vocal cord palsy
(thyroidectomy=7, lung cancer=1, others=3) and 12 normal controls underwent FDG-PET with usual protocol.
They were divided into two groups respectively; one group read books aloud for 20 minutes (phonation group)
and the other kept silence (non-phonation groups) after FDG injection. Recent neck CT scan were co-registered
with FDG-PET to produce PET-CT fusion images to elaborate small laryngeal muscles. Results: In patients with
unilateral vocal cord palsy, contralateral non-paralyzed vocal cord showed hypermetabolism mainly on
thyroarytenoid muscle, more intensely with phonation group (SUV=5.88¡¾2.65) than with non-phonation group
(SUV=2.30¡¾0.39). Normal control subjects showed hypermetabolism (3.68¡¾0.96) in interarytenoid muscle and
symmetric mild hypermetabolism in both lateral cricoarytenoid muscles in only phonation group. Conclusion:
FDG-PET with fusion images using CT scan in patients with unilateral vocal cord paralysis showed hypermetabolism
of contralateral non-paralyzed thyroarytenoid muscle, suggesting compensatory action during phonation. Phonation
during FDG-PET study enhanced FDG uptake on different laryngeal muscles between patients with unilateral vocal
cord paralysis and normal subjects. (Nucl Med Mol Imaging 2006;40(1):23-27) |
Keyword |
vocal cord palsy, 18F-FDG, fusion PET-CT |
Full text Article |
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