Abstract |
Tota1114 patients were studied prospectively with
radioiodine uptake (RAIU) and 'TcO, thyroid scan to
design a very simpte, rapid and inexpensive method
measuring the thyroid uptake on thyroid scan. After the
RAIU was obtained at 24 hours after P.O. of "'I,
Thyroid scan was perforrned at 20 minutes after I.V. of
" Tc04 and the bilateral salivary glands were included
in the scan field. Pinhole collimated and computer
assisted gamma camera was used. Three regions of
interest were set on each salivary gland and on the
thyroid by automatic edge detection method. Mean counts
per pixel were calculated for each ROI and the
salivary-thyroid rativ(STR) was defined as; STR (%)=
Mean counts per pixel of salivary glands (KC)/Mean
counts per pixel of thyroid gland (KC)*100 114 cases
consisted of 41 normal, 55 hyperthyroid and 18
hypothyroid patients and correlation between the STR
and the RAIU were evaluated in total and each group.
The STR and the RAIV showed reverse linear regression
in 114 cases (r=-0.8, P=O) and closer correlation was
showed in hyperthyroid group (r=-0.9, P=0). Mean STR in
normal group was 47.6%. In predicting the RAIU by STR,
sensitivity and specificity were 88.3% and 64.9% in 114
cases and 95.3% and 83.3% in hyperthyroid group. It is
recommended that the STR be used in place of the RAIU
giving same information at saving time, money and
radiation exposure. |