간스캔의 ROC 분석에 의한 진단적 평가 ( ROC Analysis of Diagnostic Performance in Liver Scan ) () |
Author |
이명철(Myung Chul Lee),문대혁(Dae Hyuk Moon),고창순(Chang Soon Koh),송본철(Toru Matumoto),관야지남(Yukio Tateno), |
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Abstract |
To evaluate diagnostic accuracy of liver scintigraphy
we analysed liver scans of 143 normal and 258 patients
with various liver diseases. Three ROC curves for SOL,
liver cirrhosis and diffuse liver disease were fitted
using rating methods and areas under the ROC curves and
their standard errors were calculated by the
trapezoidal rule and the variance of the Wilcoxon
statistic suggested by McNeil. We compared these
results with that of National Institute of Radiological
Science in Japan. 1) The sensitivity of liver
scintigraphy was 74.2% in SOL, 71.8% in liver cirrhosis
and 34.8% in diffuse liver disease. The specificity was
96.0% in SOL, 94.2% in liver cirrhosis and 87.6% in
diffuse liver diasease. 2) ROC curves of SOL and liver
cirrhosis approached the upper left-hand corner closer
than that of diffuse liver disease. Area (¡¾ standard
error) under the ROC curve was 0.868¡¾0.024 in SOL
and 0.867¡¾0.028 in liver cirrhosis. These were
significantly higher than 0.658¡¾0.043 in diffuse
liver disease. 3) There was no interobserver difference
in terms of ROC curves. But low sensitivty and high
specificity of authors' SOL diagnosis suggested we used
more strict decision threshold. |
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Full text Article |
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