원저 : 통상적 99mTc - DTPA 신장스캔을 이용한 GFR측정 ( Glomerular Filtration Rate Determined in Conjunction with 99mTc - DTPA Routine Renal Scintigraphy ) () |
Author |
이강욱(Gang Wook Yi),한진석(Jin Suk Han),정준기(June Key Chung),이명철(Myung Chul Lee),이정상(Jung Sang Lee),고창순(Chang Soon Koh),, |
|
Affiliation |
|
Abstract |
Many previously described nuclear medicine procedures
to assess glomerular filtration rate (GFR) required
numerous blood samples obtained over a period of
several hours to determine plasma concentrations of the
injected radiopharmaceuticals. And other indirect
methods of determining renal clearance have some
problems due to individual variations in volume of
distribution of the radionuclides used. Rescently
reported Jackson's method have the great advantages
that is a direct measurement method requiring less than
40 min of imaging time and single blood sampling. And
it correctly accounts for individual variations in
volume of distribution of the radiopharmaceuticals and
can be done with routine renal scintigraphy. We
measured Tc- 99m-DTPA renal clearance with Jackson's
method during the routine Tc-99m-DTPA renal
scintigraphy in 63 patients admitted to department of
internal medicine in SNUH. In 23 cases among 63
patients creatinine clearence was accounted
simultaneously. The range of ClDPDA was from 19.9
ml/min to 170 mi/min and the correlation of ClDPDA and
creatinine clearance was discribed by
Y=16.2570+0.7852X(X=C1DPDA, Y=creatinine clearance).
And the correlation coefficient r was 0.88. We
concluded that Tc-99m-DTPA renal clearance measurement
with Jackson's method was clinically useful to account
GFR that can be done with routine Tc-99m-DTPA renal
scintigraphy simultaneously. |
Keyword |
|
Full text Article |
28500872.pdf
|
|
|