원저 : 양전자방출단층촬영 ( PET ) 에서 회전 핀선원과 투과 및 방출 동시 영상 방법을 이용한 감쇠보정 방법 특성에 관한 고찰 ( An Assessment of Post - Injection Transmission Measurement for Attenuation Correction With Rotating Pin Sourcesin Positron Emission () |
Author |
이정림(J . R . Lee),최용(Y . Choi),이경한(K . H . Lee),김상은(S . E . Kim),지대윤(D . Y . Chi),신승애(S . A . Shin),김병태(B . T . Kim), |
|
Affiliation |
|
Abstract |
Attenuation correction is important in producing
quantitative positron emission tomography (PET) images.
Conventionally, photon attenuation effects are
corrected using transmission measurements performed
before tracer administration. The pre-injection
transmission measurement approach may require a time
delay between transmission and emission scans for the
tracer studies requiring a long uptake period, about 45
minutes for F-18 deoxyglucose study. The time delay
will limit patient throughput and increase the
1ikelihood of patient motion. A technique for
performing simultaneous transmission and emission scans
(T+E method) after the tracer injection has been
validated. The T+E method substracts the emission
counts contaminating the transmission measurements to
produce accurate attenuation correction coefficients.
This method has been evaluated in experiments using a
cylindrical phantom filled with background water (5750
cc) containing 0.4 μCi/cc of F-18 fluoride ion and one
insert cylinder (276 cc) containing 4.3 μCi/cc. GE
AdvanceTM PET scanner and Ge-68 rotating pin sources
for transmission scanning were used for this
investigation. Post-injection transmission scan and
emission scan were performed alternatively over time.
The error in emission images corrected using post-
injection transmission scan to emission images
corrected using post-injection transmission scan to
emission images corrected transmission scan was 2.6% at
the concentration of 1.0 μCi/cc. No obvious
differences in image quality and noise were apparent
between the two images. The attenuation correction can
be accomplished with post-injection transmission
measurement using rotating pin sources and this method
can significantly shorten the time between transmission
and emission scans and thereby reduce the likelihood of
patient motion and increase scanning throughput in PET. |
Keyword |
Positron Emission Tomography (PET), Attenuation correction, Transmission and emission scans |
Full text Article |
28501614.pdf
|
|
|