PET 리포터 유전자를 이용한 이행성 연구 (Translational Imaging with PET Reporter Gene Approaches) |
Author |
민정준, |
Jung-Joon Min, M.D., Ph.D. |
Affiliation |
전남대학교 의과대학 핵의학교실 Department of Nuclear Medicine, Chonnam National University Medical School, Gwangju, Korea |
Abstract |
Recent progress in the development of non-invasive imaging technologies continues to strengthen the role of biomedical research. These tools have been validated recently in variety of research models, and have been
shown to provide continuous quantitative monitoring of the location(s), magnitude, and time-variation of gene
delivery and/or expression. This article reviews the use of PET technologies as they have been used in imaging
biological processes for molecular imaging applications. The studies published to date demonstrate that noninvasive
imaging tools will help to accelerate pre-clinical model validation as well as allow for clinical monitoring of human
diseases. (Nucl Med Mol Imaging 2006;40(6):279-292) |
Keyword |
molecular imaging, positron emission tomography, gene expression, cell trafficking, gene therapy |
Full text Article |
0640060279.pdf
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